Differential association betweenMAOA, ADHD and neuropsychological functioning in boys and girls

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Differential association between MAOA, ADHD and neuropsychological functioning in boys and girls.

Attention-deficit/hyperactivity disorder (ADHD) is more common in boys than in girls. It has been hypothesized that this sex difference might be related to genes on the X-chromosome, like Monoamine Oxidase A (MAOA). Almost all studies on the role of MAOA in ADHD have focused predominantly on boys, making it unknown whether MAOA also has an effect on ADHD in girls, and few studies have investiga...

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OBJECTIVE This study investigated whether frontal lobe cortical morphology differs for boys and girls with ADHD (ages 8-12 years) in comparison to typically developing (TD) peers. METHOD Participants included 226 children between the ages of 8-12 including 93 children with ADHD (29 girls) and 133 TD children (42 girls) for which 3T MPRAGE MRI scans were obtained. A fully automated frontal lob...

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Despite the commonality of attention-deficit/hyperactivity disorder (ADHD), the diagnostic criteria are based largely on research with European American boys. Much less research is available regarding the prevalence of ADHD in other groups, specifically American Indian/Alaska Native (AI/AN) children. Moreover, research on sex differences in ADHD has typically not included AI/AN children. The cu...

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BACKGROUND Research comparing treatment-referred boys and girls with attention-deficit/hyperactivity disorder (ADHD) has yielded equivocal results. Contradictory findings may be associated with differential referral practices or unexplored interactions of gender with ADHD subtypes. METHOD We examined possible gender differences in ADHD and its subtypes among children aged 4 to 17 in a represe...

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There is vigorous debate regarding the possibility that ADHD is overdiagnosed in boys. We investigated the impact of the gender stereotype depicting boys as inattentive and impulsive on neuropsychological assessment (observation of psychology students and child's cognitive performance). In experiment 1, after the stereotype was activated, psychology students rated a "boy," a "girl," or a "child...

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ژورنال

عنوان ژورنال: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

سال: 2008

ISSN: 1552-4841,1552-485X

DOI: 10.1002/ajmg.b.30845